Yale University
|
|
|  |
|
|
Household Mold & Infant Asthma
www.pureaircontrols.com
Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma.
--Gent JF, Ren P, Belanger K, Triche E, Bracken MB, Holford TR, Leaderer BP.Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA.
We assessed prospectively the risk of increased incidence of respiratory symptoms after exposure to particular fungal genera in a susceptible population--namely, infants ((italic)n(/italic) = 880) at high risk for developing asthma. Days of wheeze or persistent cough, information on maternal allergy and asthma, socioeconomic variables, and housing characteristics were collected over the course of the infant's first year of life.
Exposure to mold was assessed by airborne samples collected at one time early in the infant's life. Fungi were identified to genus level, recorded as colony-forming units per cubic meter (CFU/m(superscript)3(/superscript)), and then categorized into four levels: 0 (undetectable), 1-499 CFU/m(superscript)3(/superscript) (low), 500-999 CFU/m(superscript)3(/superscript) (medium), and greater than or equal to 1,000 CFU/m(superscript)3(/superscript) (high). Effects of mold on wheeze and persistent cough, adjusting for potential confounding factors, were examined with Poisson regression analyses.
The two most commonly found genera were (italic)Cladosporium(/italic) (in 62% of the homes) and (italic)Penicillium(/italic) (41%). (italic)Cladosporium(/italic) was associated with reported mold ((italic)p(/italic) < 0.02) and water leaks ((italic)p(/italic) < 0.003). Rate of persistent cough was associated with reported mold [Rate ratio (RR) = 1.49; 95% CI, 1.18-1.88]. The highest level of (italic)Penicillium(/italic) was associated with higher rates of wheeze (RR = 2.15; 95% CI, 1.34-3.46) and persistent cough (RR = 2.06; 95% CI, 1.31-3.24) in models controlling for maternal history of asthma and allergy, socioeconomic status, season of mold sample, and certain housing characteristics.
We conclude that infants in this high-risk group who are exposed to high levels of (italic)Penicillium(/italic) are at significant risk for wheeze and persistent cough.
For more information contact:
Alan L. Wozniak, CIAQP
(800) 422-7873 ext. 802
iaq@pureaircontrols.com
[PRINTER FRIENDLY VERSION]
|
|
| |
|
|
|
Household Mold & Infant Asthma
|
Yale University
|
|
|
|
Pure Air Control Services Becomes 8(a) Certified
|
|
|
|
