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Hepatic Cholestasis In Patients Receiving Chronic PN
Parenteral nutrition (PN) is indicated in acute and chronic care settings when the gastrointestinal tract is neither accessible nor functional. Catheter-related sepsis, metabolic bone disease, and hepatic dysfunction are common problems in patients receiving long-term PN.1 This article will address the issue of hepatic cholestasis in patients receiving chronic PN.
[FULL STORY]
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Permissive Underfeeding With Parenteral Nutrition
Parenteral nutrition (PN) therapy has been often confused with hyperalimentation, which describes early, conscious overfeeding to minimize catabolism and hasten nutritional recovery. However, the literature is replete with studies demonstrating that feeding above energy expenditure can be associated with many deleterious sequelae, notably hyperglycemia, hepatic steatosis, and difficulty with ventilator weaning. Hypocaloric PN, in contrast, has been shown to provide clinical benefits in patients in whom enteral feeding is contraindicated, and is especially useful when volume restriction limits PN administration.
[FULL STORY]
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Editorial |
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The views expressed in MVI Newslines are those of the Editorial Board and do not necessarily represent those of aaiPharma LLC. Before prescribing any products referred to in this newsletter, please consult the accompanying full Prescribing Information or package inserts.
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