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A newly published study by British researchers finds that women who are diagnosed with an early form of breast cancer called ductal carcinoma in situ (DCIS) may be less likely to experience a recurrence of their disease if they are treated with radiation after breast cancer surgery, rather than with the drug tamoxifen. In the study, women who were treated with radiation were 60% less likely to have their cancer return after treatment, versus a reduction in risk of only 10% for the women who were treated with tamoxifen. Though there has been controversy as to whether women with early-stage breast cancer need more aggressive treatments, such as radiation, the results of this study suggest that women who receive radiation after surgery fare better than those who receive drug therapy alone.

Results from the Million Women Study, a United Kingdom research project investigating reproductive and lifestyle factors affecting women's health, has found that women who use or have used hormone replacement therapy (HRT) are more likely to develop breast cancer, compared to women who have never used HRT. This is the largest study to date linking the menopausal treatment to an increased breast cancer risk. Researchers noted that the risk of breast cancer was higher among women who used combined estrogen/progestin forms of HRT, rather than estrogen alone. The results of this study underscore the need for women to talk with their physicians before beginning/continuing an HRT regimen. Women who suffer from hot flashes or other menopausal symptoms may also wish to consider alternative remedies, depending on their personal risk of breast cancer.

Researchers have found that a gene called OPCML appears to be involved in ovarian cancer. In a recent study, the OPCML gene was found to switched off in 90% of ovarian cancer cases analyzed by researchers. Furthermore, experiments show that when a functioning OPCML is inserted into ovarian cancer tissue, the gene greatly suppresses cancer growth. The researchers say that these discoveries represent an exciting advance in ovarian cancer research which could potentially help them develop methods for preventing the disease in some women.

The results of a study by British researchers finds that older women need to be screened for cervical cancer once every five years while younger women should undergo screening once every three years. These guidelines differ from the American Cancer Society's (ACS) suggestion of a yearly Pap smear for all women who are 18 years of age or older as well as for younger women who are sexually active. In fact, the current study finds little evidence for the need to screen women under age 25, since cervical cancer rarely occurs in these women. The study offers guidance for Britain's cancer screening program.

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